Electrical characteristics of smooth muscles

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The Electrical Activity of Vascular Smooth Muscles.

岳中 典男 The electrophysiological investigation of vascular smooth muscles will permit a possible way of analyzing the mode of action of vasoactive substances. For an approach to the study the poten tial changes were recorded by means of external wick-Ag-AgC1 electrodes (1, 2). The rabbit or guinea pig aorta, dog renal artery and pig coronary artery were dissected and cut spirally. A strip prepara...

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Conduction in smooth muscles: comparative electrical properties.

BURNSTOCK, GEOFFREY AND C. L. PROSSER. Conduction in smooth muscles : comparative electrical properties. Am. J. Ph ysiol. ‘99(3) : 553-559. I g6o.-Electrical and morphological properties were correlated in a variety of mammalian smooth muscles. In the sucrose gap electrode the gut muscles (esophagus muscularis mucosae, intestinal muscles and taenia coli) showed small slow waves (5 mv) and spike...

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In-vivo Electrical Stimulation of Uterine Smooth Muscles in Sheep

An animal model was established for invivo studies of the EMG responses of a parturient uterine smooth muscle tissue to electrical stimuli. Five normally gravid sheep were fitted with implanted electrodes to register EMG signals and electrical stimulation. EMG signals were detected at the cervix and at the gravid horn. Spontaneous EMG activity was registered simultaneously with EMG responses to...

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Smooth Muscles

Results. In general, CNP and SNP exerted differential inhibitoiy effects on muscarinic-receptorinduced responses in CM and Sph isolated from the various species. Thus in bovine CM, SNP stimulated cGMP formation in a timeand concenu^ation-dependent manner and dose dependently inhibited CCh-induced IP3 production and contraction. These effects were inhibited by LY 83583, a soluble guanylyl cyclas...

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The whole plant of Biophytum petersianum was extracted with a mixture of water – alcohol (1:1) to evaluate its relaxant effect on aorta rings. In isolated Wistar rat tissue, the hydro-ethanolic extract (0.1; 0.25 and 0.5 mg/ml) non-competitively antagonized calcium chloride and high-K + - induced aorta contractions in a concentration-dependent manner. Moreover, the inhibition of noradr...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1983

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)52392-7